Preheat the oven to 400° F
In a large skillet, heat the olive oil over medium heat. Add the red onion, mushrooms, and ground venison. Cook, breaking up the meat as it cooks until the venison is browned, about 5 minutes. Be careful not to overcook the venison or it can get gamey. Add salt, pepper, garlic powder, cumin and chili powder. Remove from heat.
Arrange the chips in a single layer on a large baking sheet. Sprinkle half of the cheese over the chips and spoon the venison over top. Add the remaining cheese. Top with bell pepper, black beans, tomatoes. Bake for 10 minutes or until the cheese has melted.
Meanwhile, make the guacamole. Mix all of the ingredients in a bowl and place in the fridge to cool until the nachos are done.
Serve nachos hot out of the oven topped with guacamole, jalapeño, yogurt, cilantro and lime juice.